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PET/EVOH/PE High-Barrier Sheet for Pharmaceutical Packaging

Wallis PET/EVOH/PE pharmaceutical high-barrier sheet combines PET strength, EVOH oxygen barrier and PE heat-seal performance, with custom thickness and width for validated pharma packaging applications.
  • PET PE

  • WALLIS

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PET/EVOH/PE High-Barrier Sheet for Pharmaceutical Packaging

Wallis supplies PET/EVOH/PE high-barrier composite sheet and roll material for pharmaceutical, diagnostic, healthcare and specialty liquid packaging applications. The multilayer structure combines PET mechanical support, an EVOH oxygen-barrier layer and a PE sealing layer to support product protection, heat sealing and downstream packaging conversion.

Thickness, layer structure, roll width, color, opacity and surface requirements can be customized according to the pharmaceutical product, packaging machine, forming process, sealing conditions and target barrier performance.

For pharmaceutical applications, final suitability should be verified using the actual drug, reagent or formulation together with the intended forming, filling, sealing, sterilization, transportation and storage conditions. Barrier and compatibility requirements should therefore be defined before bulk production.

PET EVOH PE high barrier pharmaceutical packaging sheet

PET/EVOH/PE Multilayer Pharmaceutical Packaging Material

PET/EVOH/PE is a multilayer composite packaging structure designed to combine different functional properties within one material. Rather than expecting one polymer to provide every required property, each layer performs a specific role.

The PET layer contributes mechanical strength, dimensional stability and processability. EVOH is used primarily to improve oxygen and gas barrier performance. The PE layer can provide sealing functionality and contribute to moisture protection depending on the final structure.

Role of Each Layer in PET/EVOH/PE Packaging

PET Layer – Mechanical Support & Forming Performance

PET provides mechanical support, dimensional stability and a suitable base for packaging conversion. The PET layer helps the composite maintain its structure during winding, transportation, forming and filling operations.

EVOH Layer – High Oxygen Barrier

EVOH is incorporated primarily as a high oxygen and gas barrier layer. It can help reduce oxygen ingress into sensitive pharmaceutical or diagnostic products when the multilayer structure is properly designed and protected from environmental conditions that affect barrier performance.

PE Layer – Heat Sealing & Moisture Protection

PE can serve as the product-contact or sealing layer depending on the packaging design. It supports heat sealing and contributes to moisture resistance while helping protect the EVOH layer within the multilayer structure.

Technical Specifications – Typical Range

The following values represent typical specifications currently associated with this Wallis product. Final structure, thickness and performance parameters should be confirmed according to the intended pharmaceutical application.

Parameter Typical Specification / Notes
Structure PET / EVOH / PE multilayer composite
Total Thickness Approximately 80–300 µm; customizable subject to final structure
Typical Layer Range PET 60–120 µm + EVOH 15–30 µm + PE 20–40 µm; alternative ratios can be evaluated
Roll Width Approximately 30–1000 mm; customized widths available subject to production confirmation
Color / Opacity Transparent, tinted or customized opacity according to product-protection requirements
Oxygen Barrier High oxygen-barrier performance from EVOH; exact OTR should be specified with test conditions
Moisture Barrier Depends on PE layer, total structure, thickness and test conditions; confirm target WVTR during specification
Heat Sealing PE sealing layer; sealing window should be validated on the customer's equipment
Forming / Converting Thermoforming, cutting, sealing and project-specific packaging conversion subject to structure validation
Printing / Marking Batch information, expiration dates, logos and other markings with compatible inks and surface treatment
Customization Layer structure, total thickness, roll width, color, opacity, surface and packaging
PET EVOH PE pharmaceutical packaging rolls

Pharmaceutical PET/EVOH/PE Rolls

PET EVOH PE pharmaceutical packaging material

PET/EVOH/PE Pharmaceutical Packaging

Understanding OTR & WVTR for Pharmaceutical Packaging

High-barrier packaging should be specified using measurable performance requirements rather than terms such as “very low permeability” alone. Two important parameters are Oxygen Transmission Rate (OTR) and Water Vapor Transmission Rate (WVTR).

Oxygen Transmission Rate – OTR

OTR indicates how much oxygen passes through a defined area of packaging material over time. In PET/EVOH/PE structures, the EVOH layer is primarily responsible for improving oxygen-barrier performance.

Water Vapor Transmission Rate – WVTR

WVTR describes water-vapor transmission through the packaging structure. Moisture performance depends on the complete multilayer construction, including PE thickness and other structural parameters.

Always Specify Test Conditions

OTR and WVTR values should be compared only when test temperature, relative humidity, sample thickness and test method are known. Buyers should also clarify whether the stated barrier value is measured on flat material or on a formed package.

Key Advantages of PET/EVOH/PE High-Barrier Packaging

High Oxygen Barrier

The EVOH layer helps reduce oxygen permeation through the package, making the structure suitable for products where oxidation control is an important packaging requirement.

Reliable Heat-Seal Layer

PE can provide the heat-sealing interface required for many filling and sealing systems. Actual seal-initiation temperature, seal strength, dwell time and pressure should be established using the customer's equipment and mating material.

Mechanical Stability

PET contributes dimensional stability and mechanical support during winding, converting, packaging and transportation. Final stiffness depends on PET thickness and total multilayer construction.

Transparent High-Barrier Packaging

Transparent structures can allow product visibility while maintaining an oxygen-barrier layer. Tinted or more opaque structures can also be discussed where additional light management is required.

Custom Multilayer Design

Layer thickness and total structure can be adjusted according to barrier targets, forming depth, sealing requirements, product sensitivity and packaging-line conditions.

Advantages of PET EVOH PE pharmaceutical high barrier packaging

Heat-Sealing Performance & Packaging-Line Compatibility

Heat sealing is a system property rather than a material name alone. Seal performance depends on PE grade, layer thickness, sealing temperature, dwell time, pressure, mating web and packaging-machine configuration.

Define the Required Seal Window

Buyers should provide the existing packaging-machine sealing temperature range, line speed and sealing pressure where available.

Test Seal Strength

Seal strength should be tested with the actual lidding or mating material rather than evaluated from the PET/EVOH/PE forming web alone.

Evaluate Leak Resistance

Finished packs should be evaluated for seal integrity and leakage under the expected filling, transportation and storage conditions.

Thermoforming & Rigid Packaging Applications

PET/EVOH/PE composite materials can be designed for thermoforming and other converted packaging formats. Forming performance depends on total thickness, PET properties, layer adhesion, temperature profile and draw depth.

Forming Depth Matters

Barrier layers become thinner as material is stretched during thermoforming. Therefore, barrier performance measured on a flat roll cannot automatically be assumed to be identical at the deepest part of a formed cavity.

Validate Formed-Part Barrier

Where barrier performance is critical, buyers should validate the formed package under representative forming conditions rather than relying only on flat-sheet OTR or WVTR data.

Confirm Forming Temperature & Cycle

Provide the thermoforming equipment type, mold depth, line speed and expected forming-temperature window when discussing a customized structure.

Recommended Pharmaceutical & Healthcare Applications

Pharmaceutical Liquid Packaging

PET/EVOH/PE structures can be evaluated for pharmaceutical liquid packaging where oxygen barrier, seal integrity and product compatibility are required.

Diagnostic & Laboratory Reagents

Diagnostic liquids and reagents may benefit from high-barrier packaging, but compatibility testing should be conducted using the specific reagent composition and intended storage conditions.

Oxygen-Sensitive Formulations

Products sensitive to oxidative degradation can be candidates for packaging structures containing an EVOH oxygen-barrier layer, subject to shelf-life and stability validation.

Light-Sensitive Products

Tinted or opaque structures can be discussed for products that require reduced light transmission. The required wavelength protection should be defined according to the pharmaceutical formulation.

Nutraceutical & Specialty Healthcare Packaging

Customized barrier structures may also be evaluated for vitamins, nutraceutical liquids, diagnostic products and other healthcare applications requiring controlled oxygen and moisture exposure.

High barrier packaging for vitamin and antioxidant solutions

Vitamin or Antioxidant Solutions

PET EVOH PE packaging application for pharmaceutical liquids

Pharmaceutical Liquid Applications

High barrier packaging for diagnostic and chemical reagents

Diagnostic & Chemical Reagents

Pharmaceutical Product Compatibility Must Be Validated

PET/EVOH/PE should not be described as universally compatible with every pharmaceutical API, solvent, reagent or formulation. Product-contact suitability depends on the exact PE layer, additives, drug composition, concentration, pH, storage time and temperature.

Chemical Compatibility Testing

Buyers should evaluate dimensional stability, swelling, extraction, seal integrity and barrier retention after contact with the intended formulation.

Migration & Extractables Requirements

Where regulatory or pharmaceutical quality systems require migration, extractables, leachables or toxicological evaluation, the applicable test protocol should be defined for the finished packaging system.

Shelf-Life Validation

High-barrier material can support product protection, but final drug shelf life must be established through the pharmaceutical manufacturer's stability program. Packaging material alone cannot guarantee a specific shelf life.

Sterilization Compatibility

Sterilization compatibility depends on the exact PET/EVOH/PE construction and the sterilization process. A material should not automatically be considered compatible with autoclave, dry heat, radiation, ethylene oxide or other sterilization methods without validation.

Buyers should provide the sterilization technology, temperature, exposure time, pressure and number of cycles. The finished package should then be evaluated for deformation, layer adhesion, seal strength, barrier retention and product compatibility.

Regulatory & Quality Documentation

Pharmaceutical packaging requirements vary by country, product type and dosage form. Instead of relying on a generic statement such as “pharmaceutical compliant,” buyers should specify the exact regulatory, pharmacopoeial or customer quality requirements applicable to the project.

Documentation requirements may include material specifications, certificates of analysis, composition statements, quality-system documentation, migration testing or other records depending on the destination market and pharmaceutical manufacturer's qualification process.

Why Choose Wallis PET/EVOH/PE High-Barrier Rolls?

Customized Barrier Structure

Layer ratios can be discussed according to target OTR, WVTR, total thickness, forming performance and heat-sealing requirements.

Custom Width & Thickness

Roll dimensions can be matched to the customer's packaging and converting equipment to reduce unnecessary slitting, handling and material waste.

Sample Evaluation Before Bulk Orders

Samples can be evaluated for barrier performance, heat-seal behavior, forming, dimensional stability and product compatibility before commercial production.

B2B & OEM Supply

Wallis supports pharmaceutical packaging converters, medical packaging companies, diagnostic manufacturers and other industrial buyers requiring customized multilayer packaging materials.

Wallis pharmaceutical packaging material factory

Pharmaceutical Packaging Material Factory

Pharmaceutical packaging material inspection room

Pharmaceutical Packaging Inspection Room

Pharmaceutical composite packaging production line

Pharmaceutical Material Packaging Production Line

Wallis pharmaceutical packaging material production line

Pharmaceutical Packaging Material Production Line

What Information Should Buyers Provide for a Quotation?

Packaging Application

Describe the pharmaceutical, diagnostic or healthcare product and the finished package format.

Required Structure

Specify PET/EVOH/PE or provide your existing multilayer structure if you need an equivalent or optimized material.

Thickness & Layer Ratio

Provide total thickness and individual layer requirements where already defined.

Target OTR & WVTR

Provide target barrier values together with test temperature, relative humidity and test method wherever possible.

Roll Width

Specify the required roll width, roll diameter or weight and core requirements according to the packaging line.

Thermoforming Conditions

Provide cavity dimensions, draw depth, forming equipment and operating conditions if the material will be thermoformed.

Heat-Sealing Conditions

Include the mating material, seal temperature, pressure, dwell time and line speed if already known.

Product-Contact Requirements

Identify the pharmaceutical formulation or chemical-contact conditions that need to be considered during compatibility testing.

Sterilization Requirements

If sterilization is required, specify the exact process and cycle conditions so material suitability can be evaluated.

Regulatory Requirements

Provide the destination country, required standards and documentation expected by your regulatory or quality team.

Estimated Order Quantity

Current product information indicates a typical starting MOQ around 500 kg, although final MOQ depends on customized layer structure, dimensions and production requirements.

About Shanghai Wallis Technology Co., Ltd.

Shanghai Wallis Technology supplies plastic sheet, card material and specialty packaging materials to international B2B customers. Pharmaceutical packaging projects can be discussed according to required structure, performance, production-line conditions and customer qualification procedures.

Why Manufacturers Work with Wallis

  • Customized multilayer material development

  • Thickness and width customization

  • Sample support for packaging-line evaluation

  • B2B and OEM production support

  • Export packaging and international supply

  • Technical specification discussion before bulk production

Shanghai Wallis pharmaceutical packaging team

Customer Reviews

Wallis pharmaceutical packaging customer reviews

Wallis customer feedback for plastic packaging materials

FAQ About PET/EVOH/PE Pharmaceutical Packaging

What is PET/EVOH/PE pharmaceutical packaging?

PET/EVOH/PE is a multilayer plastic packaging structure combining PET mechanical properties, EVOH oxygen-barrier performance and a PE layer for sealing and moisture protection. The layer ratios can be adjusted according to the required packaging performance.

What is the purpose of EVOH in pharmaceutical packaging?

EVOH is primarily used to improve oxygen and gas barrier performance. It can help protect oxygen-sensitive products when integrated into a properly designed multilayer structure.

Does EVOH provide the moisture barrier?

EVOH is mainly selected for oxygen barrier performance. Moisture-barrier performance depends on the complete multilayer structure, including PE and other protective layers, their thicknesses and the test conditions.

What thicknesses are available?

The current Wallis product range lists approximately 80–300 µm total thickness. Customized structures can be discussed according to barrier, forming and sealing requirements.

What roll widths are available?

The current typical range is approximately 30–1000 mm. Final width availability depends on structure, thickness and production requirements.

What OTR should I specify?

The required OTR depends on the oxygen sensitivity of the packaged product, shelf-life target and package geometry. Provide the target OTR together with temperature, relative humidity and test method so materials can be compared correctly.

What WVTR should I specify?

The required WVTR depends on the moisture sensitivity of the product and expected storage environment. Test temperature, humidity and package configuration should be specified together with the target value.

Can PET/EVOH/PE be thermoformed?

Suitable structures can be designed for thermoforming, but forming temperature, draw depth, layer adhesion and barrier retention should be evaluated using the actual package geometry and production conditions.

Can the material be heat sealed?

The PE layer can provide heat-sealing functionality. Seal strength and seal temperature should be validated with the mating material and actual filling and sealing equipment.

Is PET/EVOH/PE compatible with all pharmaceutical liquids?

No universal compatibility claim should be made for all pharmaceutical liquids. Compatibility depends on the formulation, PE contact layer, concentration, pH, temperature and storage duration. Product-contact testing is recommended.

Is this material compatible with autoclave sterilization?

Sterilization compatibility must be confirmed for the exact multilayer structure and cycle. Provide sterilization temperature, pressure, duration and number of cycles so the material and finished seal can be evaluated.

Can the sheet be tinted for light-sensitive products?

Tinted or customized-opacity structures can be discussed. Buyers should provide the required light-protection specification or product sensitivity information for evaluation.

Is PET/EVOH/PE pharmaceutical packaging fully regulatory compliant?

Compliance depends on the exact material structure, pharmaceutical application and destination market. Buyers should provide the applicable regulatory or pharmacopoeial requirements so available documentation and testing can be reviewed for the specific product.

Can Wallis provide samples?

Samples can be discussed for evaluating thickness, barrier performance, heat sealing, thermoforming and compatibility with the customer's packaging equipment and product.

What is the MOQ?

Current product information indicates a typical starting quantity around 500 kg. Customized structure, width, color and other requirements can affect the final MOQ, so it should be confirmed during quotation.

What information should I provide for a quotation?

Please provide the packaging application, product type, required structure, thickness, roll width, target OTR and WVTR, forming conditions, heat-seal conditions, sterilization process, regulatory requirements and estimated order quantity.

Looking for a PET/EVOH/PE Pharmaceutical Packaging Supplier?

Send Wallis your required multilayer structure, thickness, roll width, OTR/WVTR target, forming process, heat-sealing conditions, product-contact requirements and estimated purchasing quantity.

If you are replacing an existing pharmaceutical packaging material, send the current technical specification or sample so the structure and packaging-line requirements can be evaluated before commercial production.

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